Recently, we had an overview of a new world of anabolic compounds that show potential to become an important part of the chemical enhancement arsenal at our disposal. These new and amazing compounds are Selective Androgen Receptor Modulators or SARMs for short. Here’s a link to the overview article in case you missed it: Selective Androgen Receptor Modulators or SARMs. Now, we will take a look at a specific SARM known as S-4 a.k.a. Acetamidoxolutamide.
S4 (Acetamidoxolutamide) as it is known, is a a selective androgen receptor modulator or SARM for short. When compared to anabolic steroids, S4 is a selective androgen receptor modulator with one of the most androgenic effects. This androgenic effect is that S4 is 1/3rd the strength of testosterone when binding to androgen receptors. S4 is fast acting and its half life is 4 hours. It may be able to reduce the size of the prostate if used at a honest dosage which is why SARMs are being looked at as replacement for Androgen Deprived Therapy or ADT for short.
One of S4’s best attributes is the fact that it causes a drying out and hardening appearance of the muscle along with tightening of the skin. It binds extremely well to your androgen muscle tissue receptors (AR), leading to more lean body mass which is why you as a bodybuilder would want to learn about it the first place.
Another great attribute is that S4 promotes dramatic fat loss by binding to your androgen receptors causing your fat to be oxidized. Part of the reason why one dries out so well while using it is because since it is not an androgen it does not aromatize. This means that S4 cannot turn into any of the nasty estrogenic hormones that cause problems, the way anabolic steroids do.
An oral dose of between 30mg to 50mg per day is what is needed to see results.
Unfortunately, S4 use is not without dangers. S4 can turn into the metabolite known as “M1”, a compound which could possibly cause a change in one’s own DNA. How does the S4 metabolite M1 affect the user? M1 can bind to the ocular receptor in your eye and it can bind to receptors in your heart the same way. This can have an averse impact on your vision, heart and other organs. This is why it is common to hear feedback from S4 testing stating that a subject\’s vision became all one color at night. We can speculate that so long as one is careful and does not abuse S4, there is likely no real long term serious threat. Short term usage is probably acceptable, but long term use of S4 is not recommended until further clinical trials are performed.
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Here’s another article about SARMs S-4 on EliteFitness.com:
And here are some of the many discussions about SARMs S-4 on the EliteFitness.com Forums:
And here\’s a link to my article on SARM S-1: a.k.a. Ostarine or MK 2866. Use this link to discover how bodybuilders are using S-1. And I\’ll also tell you about how bodybuilders and athletes are using SARMs as a bridge between anabolic steroid cycles in order to maintain and increase muscle gains.